Systems biology: The reincarnation of systems theory applied in biology?

Systems Biology: the Reincarnation of Systems Theory Applied in Biology?

With the availability of quantitative data on the transcriptome and proteome level, there is an increasing interest in formal mathematical models of gene expression and regulation. International conferences, research institutes and research groups concerned with systems biology have appeared in recent years and systems theory, the study of organisation and behaviour per se, is indeed a natural ...

Systems biology and the biology of systems.

When I sit down to write an editorial for Physiology, I flatter myself that the two or three people who will ultimately read it want to hear my thoughts on a “big” topic. It strikes me that, within the rarefied realm of academic biology, there few bigger topics, or at least few topics more all encompassing in their scope, than Systems Biology. Perhaps it is the ambiguity inherent in its name th...

Control Theory and Systems Biology

Systems biology reveals biology of systems

In the last decades, genomic and postgenomic technologies obtained a great amount of information on molecular bases of cell physiology and organization. In spite of this, the knowledge of cells and living organisms in their entirety, is far from being achieved. In order to deal with biological complexity, Systems Biology uses a new approach to overcome this inadequacy. Despite different definit...

Systems Biology Approaches Applied to Regenerative Medicine

Systems biology is the creation of theoretical and mathematical models for the study of biological systems, as an engine for hypothesis generation and to provide context to experimental data. It is underpinned by the collection and analysis of complex datasets from different biological systems, including global gene, RNA, protein and metabolite profiles. Regenerative medicine seeks to replace o...